Low seroprevalence of Ebola virus in health care providers in an endemic region (Tshuapa province) of the Democratic Republic of the Congo.

Trésor Zola MatuvangaJoachim MariënYnke LarivièreBernard Isekah Osang'irSolange MiloloRachel MetaEmmanuel EsangaVivi MaketaJunior MatangilaPatrick MitashiSteve Ahuka MundekeHypolite Muhindo-MavokoJean-Jacques Muyembe TamfumPierre Van DammeJean-Pierre Van Geertruyden

Published in: PloS one (2023)

In contrast to previous serosurveys, a low seroprevalence was found in the HCP and frontline population participating in the EBL2007 Ebola vaccine trial in Boende, DRC. This underscores the high need for standardized antibody assays and cutoffs in EBOV serosurveys to avoid the broad range of reported EBOV seroprevalence rates in EBOV endemic areas.

Keyphrases

healthcare
magnetic resonance
south africa
clinical trial
study protocol
high throughput
phase iii
phase ii
magnetic resonance imaging
computed tomography