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Dual-targeting liposomes modified with BTP-7 and pHA for combined delivery of TCPP and TMZ to enhance the anti-tumour effect in glioblastoma cells.

Lili LiLin JingZijun TangJingguo DuYonglong ZhongXu LiuMingqing Yuan
Published in: Journal of microencapsulation (2024)
BTP-7/pHA-TMZ/TCPP-Lip can specifically target the tumour cells to achieve efficient drug delivery, and improve the anti-tumour efficacy and reduces the systemic toxicity.
Keyphrases
  • drug delivery
  • induced apoptosis
  • cell cycle arrest
  • oxidative stress
  • endoplasmic reticulum stress
  • signaling pathway
  • drug release
  • pi k akt