Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study.
Carin NorthuisElizabeth BellPamela L LutseyKristen M GeorgeRebecca F GottesmanTom H MosleyEric A WhitselKamakshi LakshminarayanPublished in: Neurology (2023)
This study provides Class III evidence that use of prescribed PPIs for > 4.4 years by individuals ages 45 years and older is associated with a higher incidence of newly diagnosed dementia.