Overexpression of SNTG2, TRAF3IP2, and ITGA6 transcripts is associated with osteoporotic vertebral fracture in elderly women from community.
Levi H Jales NetoZofia WicikGeorgea H F TorresLiliam TakayamaValéria F CaparboNeuza H M LopesAlexandre C PereiraRosa Maria Rodrigues PereiraPublished in: Molecular genetics & genomic medicine (2020)
Our data identified and validated the association of SNTG2 (608715), TRAF3IP2 (607043), and ITGA6 (147556) with osteoporotic VF in elderly women, independently of BMD. These results suggest that these transcripts have potential clinical significance and may help to explain the molecular mechanisms and biological functions of vertebral fracture.
Keyphrases
- bone mineral density
- polycystic ovary syndrome
- postmenopausal women
- middle aged
- pregnancy outcomes
- community dwelling
- healthcare
- cervical cancer screening
- mental health
- cell proliferation
- hip fracture
- transcription factor
- risk assessment
- type diabetes
- pregnant women
- machine learning
- human health
- climate change
- metabolic syndrome