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Nuclear Cross-Section of Proton-Induced Reactions on Enriched 48 Ti Targets for the Production of Theranostic 47 Sc Radionuclide, 46c Sc, 44m Sc, 44g Sc, 43 Sc, and 48 V.

Liliana MouLucia De DominicisSara CisterninoHanna SkliarovaMatteo CampostriniValentino RigatoLaura De NardoLaura Melendez-AlafortJuan EspositoFérid HaddadGaia Pupillo
Published in: Pharmaceuticals (Basel, Switzerland) (2023)
The cross-sections of the 48 Ti(p,x) 47 Sc, 46c Sc, 44m Sc, 44g Sc, 43 Sc, and 48 V nuclear reactions were measured from 18 to 70 MeV, with particular attention to 47 Sc production. Enriched 48 Ti powder was deposited on an aluminum backing and the obtained targets were characterized via elastic backscattering spectroscopy at the INFN-LNL. Targets were exposed to low-intensity proton irradiation using the stacked-foils technique at the ARRONAX facility. Activated samples were measured using γ-spectrometry; the results were compared with the data int he literature and the theoretical TALYS-based values. A regular trend in the new values obtained from the different irradiation runs was noted, as well as a good agreement with the literature data, for all the radionuclides of interest: 47 Sc, 46c Sc, 44m Sc, 44g Sc, 43 Sc, and 48 V. 47 Sc production was also discussed, considering yield and radionuclidic purity, for different 47 Sc production scenarios.
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