Bergmann glia translocation: a new disease marker for vanishing white matter identifies therapeutic effects of Guanabenz treatment.

Stephanie DoovesM BugianiL E WisseT E M AbbinkM S van der KnaapV M Heine

Published in: Neuropathology and applied neurobiology (2017)

Bergmann glia translocation can be used to objectively assess effects of treatment in VWM mice. Future treatment strategies involving compounds regulating eIF2 phosphorylation might benefit VWM patients.

Keyphrases

white matter
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
gene expression
type diabetes
prognostic factors
metabolic syndrome
multiple sclerosis
adipose tissue
dna methylation
current status
patient reported outcomes
insulin resistance