Gray matter density reduction associated with adjuvant chemotherapy in older women with breast cancer.
Bihong T ChenTaihao JinSunita K PatelNingrong YeCan-Lan SunHuiyan MaRussell C RockneJames C RootAndrew J SaykinTim A AhlesAndrei I HolodnyNeal PrakashJoanne MortimerJames WaismanYuan YuanDaneng LiGeorge SomloJessica VazquezAbrahm LeviHeidi TanRichard YangVani KatheriaArti HurriaPublished in: Breast cancer research and treatment (2018)
Our findings indicate that GMD reductions were associated with adjuvant chemotherapy in older women with breast cancer. Future studies are needed to understand the clinical significance of the neuroimaging findings. This study is registered on ClinicalTrials.gov (NCT01992432).