Fucosyltransferase 5 Promotes the Proliferative and Migratory Properties of Intrahepatic Cholangiocarcinoma Cells via Regulating Protein Glycosylation Profiles.

Jingheng GuoQian ChengYongjian LiLingyu TianDelin MaZhao LiJie GaoJiye Zhu

Published in: Clinical Medicine Insights. Oncology (2023)

FUT5 is upregulated in ICC and promotes ICC development by promoting glycosylation of several proteins. Therefore, FUT5 may serve as a therapeutic target for the treatment of ICC.

Keyphrases

induced apoptosis
cell cycle arrest
cell death
protein protein
combination therapy
amino acid
binding protein
cell proliferation
pi k akt