Potential impact on cost-effectiveness estimates of using immature survival data: a case study based on transcatheter edge-to-edge repair (TEER) used for patients with severe mitral regurgitation at high surgical risk.

Martin ConnockPeter AugusteAude CapelleAnna-Maria HénaineJean-François ObadiaXavier Armoiry

Published in: BMJ open (2023)

Modelling survival in such small samples followed up for only 12 months is associated with great uncertainty, and cost-effectiveness results based on these analyses should be viewed as premature and used cautiously in reimbursement decisions.

Keyphrases

free survival
early onset
big data
machine learning
climate change
deep learning
drug induced
data analysis