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Sleep disturbances, cognitive decline, and AD biomarkers alterations in early Parkinson's disease.

Zhong RuiCaiting GanHuimin SunKe-Zhong Zhang
Published in: Annals of clinical and translational neurology (2024)
Sleep disturbances (i.e., pRBD, EDS, and insomnia) were associated with cognitive decline in early PD. EDS and pRBD were associated with decrease of CSF Aβ42. Moreover, pRBD was associated with conversion to dementia.
Keyphrases
  • cognitive decline
  • mild cognitive impairment
  • sleep quality
  • physical activity