Effects of Previous Infection and Vaccination on Symptomatic Omicron Infections.
Heba N AltarawnehHiam ChemaitellyHoussein H AyoubPatrick TangMohammad R HasanHadi M YassineHebah A Al-KhatibMaria K SmattiPeter CoyleZaina Al-KanaaniEinas Al-KuwariAndrew M JeremijenkoAnvar H KaleeckalAli N LatifRiyazuddin M ShaikHanan F Abdul-RahimGheyath K NasrallahMohamed G Al-KuwariAdeel Ajwad ButtHamad E Al-RomaihiMohamed H Al-ThaniAbdullatif Al-KhalRoberto BertolliniLaith Jamal Abu-RaddadPublished in: The New England journal of medicine (2022)
No discernable differences in protection against symptomatic BA.1 and BA.2 infection were seen with previous infection, vaccination, and hybrid immunity. Vaccination enhanced protection among persons who had had a previous infection. Hybrid immunity resulting from previous infection and recent booster vaccination conferred the strongest protection. (Funded by Weill Cornell Medicine-Qatar and others.).
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