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Limited clinical role of blood eosinophil levels in early life atopic disease: A mother-child cohort study.

Signe Kjeldgaard JensenMathias Elsner MelgaardCasper-Emil Tingskov PedersenLuo YangNilo VahmanJacob Pontoppidan ThyssenAnn-Marie Malby SchoosJakob StokholmHans BisgaardBo Lund ChawesKlaus Bønnelykke
Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2023)
Blood eosinophil count at 18 months was not associated with current wheezing/asthma or atopic dermatitis and did not predict persistence or development of disease. This implies a limited clinical role of blood eosinophil levels in early-life atopic disease and questions the clinical value of blood eosinophil counts measured in toddlers as a predictive biomarker for subsequent atopic disease in early childhood.
Keyphrases
  • early life
  • atopic dermatitis
  • chronic obstructive pulmonary disease
  • peripheral blood
  • lung function