A Retrospective Database Study of Gastrointestinal Events and Medical Costs Associated with Nonsteroidal Anti-Inflammatory Drugs in Japanese Patients of Working Age with Osteoarthritis and Chronic Low Back Pain.
Shogo KikuchiKanae TogoNozomi EbataKoichi FujiiNaohiro YonemotoLucy AbrahamTakayuki KatsunoPublished in: Pain medicine (Malden, Mass.) (2021)
NSAID-associated GI toxicity imposes a significant health and economic burden on patients with OA and/or CLBP, irrespective of whether oral or topical NSAIDs are used.