Feasibility of using megavoltage computed tomography to reduce proton range uncertainty: A simulation study.
Yanle HuXiaoning DingJiajian ShenMartin BuesWei LiuYixiu KangShuai LengLifeng YuPublished in: Journal of applied clinical medical physics (2021)
Chemical composition had a negligible effect on the method of using RED to determine proton SPR. RED itself is sufficient to accurately determine proton SPR. MVCT number maintains a superb linear relationship with RED because it is highly dominated by Compton scattering. Therefore, MVCT has great potential in reducing the proton range uncertainty.