Sequential Prostate Magnetic Resonance Imaging in Newly Diagnosed High-risk Prostate Cancer Treated with Neoadjuvant Enzalutamide is Predictive of Therapeutic Response.
Fatima KarzaiStephanie M WalkerScott WilkinsonRavi A MadanJoanna H ShihMaria J MerinoStephanie A HarmonDavid J VanderWeeleLisa M CordesNicole V CarrabbaJohn R BrightNicholas T TerriginoGuinevere ChunMarijo BilusicAnna CouvillonAmy HankinMonique N WilliamsRosina T LisHuihui YePeter L ChoykeJames L GulleyAdam G SowalskyBaris TurkbeyPeter A PintoWilliam L DahutPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Low relative lesion volume at baseline mpMRI was predictive of pathologic response. A subset of patients had limited response. Selection of patients based on these metrics may improve outcomes in high-risk disease.