Assessing the impact of MRI based diagnostics on pre-treatment disease classification and prognostic model performance in men diagnosed with new prostate cancer from an unscreened population.
Artitaya LophatananonMatthew H V ByrneTristan BarrettAnne WarrenKenneth MuirIbifuro DokuboFanos GeorgiadesMostafa ShebaLisa BibbyVincent J GnanapragasamPublished in: BMC cancer (2022)
MRI guided diagnostics does change pre-treatment risk groups assignments but the overall prognostic impact appears modest in men referred from unscreened populations. Particularly, when using more granular tiers or individualised prognostic models. Existing risk and prognostic models can continue to be used to counsel men about treatment option until long term survival outcomes are available.