Hypermigration of macrophages through the concerted action of GRA effectors on NF-κB/p38 signaling and host chromatin accessibility potentiates Toxoplasma dissemination.
Arne L Ten HoeveMatias E RodriguezMartin SäflundValentine MichelLucas MagimelAlbert RipollTianxiong YuMohamed-Ali HakimiJeroen P J SaeijDeniz M OzataAntonio BarraganPublished in: mBio (2024)
can orchestrate a complex biological phenotype, such as the migratory activation of phagocytes to boost dissemination.