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Comparing the Efficacy of Two Cognitive Screening Tools in Identifying Gray and White Matter Brain Damage among Older Adults.

Paula Andreatta MaduroManoel Pereira GuimarãesMateus de Sousa RodriguesAna Paula Pereira Rolim Coimbra PintoAmérico Alves da Mota JuniorAlaine Souza Lima RochaJuliana Magalhães Duarte MatosoBruno Bavaresco GambassiFernando Martins Carvalho
Published in: Journal of aging research (2024)
The MMSE and MoCA screening tools effectively identified gray and white matter brain damage in older adults with varying degrees of cognitive impairment. Lower MMSE scores are associated with MTL atrophy and lesions, and lower MoCA scores are related to PWM lesions. The concurrent use of MMSE and MoCA is recommended for assessing structural changes in distinct brain regions.
Keyphrases
  • white matter
  • multiple sclerosis
  • cognitive impairment
  • oxidative stress
  • resting state
  • physical activity
  • cerebral ischemia
  • blood brain barrier