Fe3O4 magnetic nanoparticle-enhanced radiotherapy for lung adenocarcinoma via delivery of siBIRC5 and AS-ODN.

Shuzhen ChenFushi HanDongdong HuangJinqian MengJiapeng ChuMeng WangPei-Jun Wang

Published in: Journal of translational medicine (2021)

Findings obtained in our study indicated that Fe3O4 MNPs-targeted delivery of siBIRC5 and AS-ODN enhances radiosensitivity, providing an innovative solution for the current clinically existing lung adenocarcinoma patients with radiotherapy resistance with a low risk of toxicity.

Keyphrases

early stage
locally advanced
radiation therapy
radiation induced
oxidative stress
squamous cell carcinoma
molecularly imprinted
iron oxide