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CD47 Activation by Thrombospondin-1 in Lymphatic Endothelial Cells Suppresses Lymphangiogenesis and Promotes Atherosclerosis.

Bhupesh SinglaRavi Varma AithbathulaNaveed PervaizIshita KathuriaMallory SwansonFrederick Adams EkubanWonMo AhnFrank ParkMaxwell GyamfiMary Cherian-ShawUdai P SinghSantosh Kumar
Published in: Arteriosclerosis, thrombosis, and vascular biology (2023)
attenuates atherosclerotic lesion formation. Collectively, these results identify LEC CD47 as a potential therapeutic target in atherosclerosis.
Keyphrases
  • endothelial cells
  • cardiovascular disease
  • lymph node
  • nk cells
  • signaling pathway
  • high glucose
  • vascular endothelial growth factor
  • human health