The decisive role of molecular pathology in presumed somatic metastases of type II testicular germ cell tumors: report of 2 cases.

Mariëtte E G KranendonkWenzel M HackengG Johan A OfferhausFolkert H M MorsinkGeertruida N JongesGerard GroenewegenPieter-Jaap KrijtenburgHeinz-Josef KlümpenWendy W J de LengLeendert H J LooijengaLodewijk A A Brosens

Published in: Diagnostic pathology (2020)

Without the molecular data, both cases would have been regarded as a metastatic TGCT with development of somatic-type malignancy, which appeared a wrong diagnosis for case 2. These cases demonstrate the importance of molecular methods as an adjunct in today's pathology practice.

Keyphrases

germ cell
healthcare
squamous cell carcinoma
primary care
copy number
big data
genome wide