Association of adverse childhood experiences with adulthood multiple sclerosis: A systematic review of observational studies.
Syeda Tayyaba RehanZayeema KhanSyed Hasan ShujaAfia SalmanHassan Ul HussainMuhammad Saif AbbasiSufyan RazakHuzaifa Ahmad CheemaSarya SwedSalim SuraniPublished in: Brain and behavior (2023)
Results support a significant association between ACEs and the development of MS; individuals with a positive history of ACEs develop MS symptoms earlier. Moreover, the severity of ACEs is also linked with increased relapse rates of MS.