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Modelling impact and cost-effectiveness of oral pre-exposure prophylaxis in 13 low-resource countries.

Carel PretoriusMelissa SchnureJuan DentRobert GlaubiusGuy MahianeMatthew HamiltonMeghan ReidySindy MatseEmmanuel NjeuhmeliDelivette CastorKatharine E Kripke
Published in: Journal of the International AIDS Society (2020)
These modelling results can inform prioritization, target-setting and other decisions related to oral PrEP scale-up within combination prevention programmes. We caution against extensive use given limitations in cost data and implementation approaches. This analysis highlights some of the immediate challenges facing countries-for example, trade-offs between overall impact and cost-effectiveness-and emphasizes the need to improve data availability and risk assessment tools to help countries make informed decisions.
Keyphrases
  • risk assessment
  • electronic health record
  • primary care
  • big data
  • healthcare
  • men who have sex with men
  • heavy metals
  • quality improvement
  • machine learning
  • human health