Single-cell RNA sequencing reveals intrahepatic and peripheral immune characteristics related to disease phases in HBV-infected patients.

Chao ZhangJiesheng LiYongqian ChengFanping MengJin-Wen SongXing FanHongtao FanJing LiYu-Long FuMing-Ju ZhouWei HuSi-Yu WangYuan-Jie FuJi-Yuan ZhangRuo-Nan XuMing ShiXueda HuZemin ZhangXianwen RenFu-Sheng Wang

Published in: Gut (2022)

Our study dissects the coordinated immune responses for different HBV infection phases and provides a rich resource for fully understanding immunopathogenesis and developing effective therapeutic strategies.

Keyphrases

single cell
hepatitis b virus
immune response
rna seq
liver failure
high throughput
dendritic cells
chemotherapy induced