Proton pencil beam scanning reduces secondary cancer risk in breast cancer patients with internal mammary chain involvement compared to photon radiotherapy.

Giorgio CartechiniFrancesco FracchiollaLoris MenegottiEmanuele ScifoniChiara La TessaMarco SchwarzPaolo FaraceFrancesco Tommasino

Published in: Radiation oncology (London, England) (2020)

PBS PT is associated to significant SCR reduction in BC patients compared to photon radiotherapy. The benefits are maximized for young patients with both SVC and IMNs involvement. When combined with the improved sparing of the heart, this might contribute to the establishment of effective patient-selection criteria for proton BC treatments.

Keyphrases

early stage
end stage renal disease
ejection fraction
radiation therapy
newly diagnosed
locally advanced
chronic kidney disease
heart failure
radiation induced
prognostic factors
high resolution
living cells
electron microscopy
robot assisted
mass spectrometry
patient reported