Pathogenic variants screening in seventeen candidate genes on 2p15 for association with ankylosing spondylitis in a Han Chinese population.

Mengmeng WangLihong XinGuoqi CaiXu ZhangXiao YangXiaona LiQing XiaLi WangShengqian XuJianhua XuZongwen ShuaiChanghai DingFa-Ming Pan

Published in: PloS one (2017)

rs14170 and rs2123111 inUSP34 and rs1729674 in C2orf74 may be associated with AS susceptibility in Han Chinese population. USP34 and C2orf74 in 2p15 region may be AS novel susceptibility genes.

Keyphrases

ankylosing spondylitis
rheumatoid arthritis
disease activity
genome wide
copy number
bioinformatics analysis