Maternal body mass index and placental weight: a role for fetal insulin, maternal insulin and leptin.
Oddrun KristiansenMarie Cecilie Paasche RolandManuela ZucknickTrine M ReineSvein O KolsetT HenriksenTove LekvaTrond Melbye MichelsenPublished in: Journal of endocrinological investigation (2022)
The BMI-PW association was non-linear: an association was observed for BMI <25 but not for BMI ≥25. Leptin may be involved in the non-linear association through a placental-adipose tissue interplay. Maternal early pregnancy insulin and fetal insulin at term were associated with PW.