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"An Unusual Pattern of Metastasis" Metastatic Malignant Thymoma Presented with Breast Lump: A Case Report and Literature Review.

Kah Seng KhooKavinya Diana T NadesalingamDiana Bee-Lan OngLi-Ying TeohMei-Sze TehSuniza JamarisMee-Hoong See
Published in: Case reports in surgery (2023)
Metastatic lesions to the breast from extramammary malignant neoplasms are rare and reported account for 0.5-6.6% of all breast malignancies. Distant metastasis of thymoma is even rarer, especially to extrathoracic regions. We reported a woman with invasive malignant thymoma postneoadjuvant and resection of the thymoma, who developed breast metastasis 7 years later. Breast imaging showed high-density lesion with no intralesional microcalcifications and no significant axillary lymphadenopathy. Core biopsy and histopathology proved the lesion to be metastatic thymic carcinoma. Despite rarity, breast lumps with underlying extramammary malignancy should raise the suspicious of breast metastasis.
Keyphrases
  • squamous cell carcinoma
  • small cell lung cancer
  • high density
  • lymph node
  • high resolution
  • early stage
  • neoadjuvant chemotherapy
  • myasthenia gravis
  • mass spectrometry