Conventionally fractionated radiation therapy versus stereotactic body radiation therapy for locally advanced pancreatic cancer (CRiSP): An international systematic review and meta-analysis.
Leila T TchelebiEric J LehrerDaniel M TrifilettiNavesh K SharmaMatthew E B DixonChristopher H CraneNicholas G ZaorskyPublished in: Cancer (2020)
These results suggest that SBRT for LAPC may result in a modest improvement in 2-year OS with decreased rates of acute grade 3/4 toxicity and no change in 1-year-OS or late toxicity. Further study into the use of stereotactic body radiation therapy for these patients is needed.