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Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery.

Chuang ZhaoKadalipura P RakeshSaira MumtazBalakrishna MokuAbdullah Mohammed AsiriHadi M MarwaniManukumar Honnayakanahalli MarichannegowdaHua-Li Qin
Published in: RSC advances (2018)
Arylnaphthalene lactones are natural products extracted from a wide range of different parts of plants. The progressing interest in the synthesis of these compounds is due to their significant biological activities, which have made them potential candidates in drug discovery and development. This review mainly covers recent developments in the synthesis and biological applications of arylnaphthalene lactone analogs.
Keyphrases
  • drug discovery
  • molecular docking
  • current status
  • molecular dynamics simulations
  • structure activity relationship