Avoiding scar tissue formation of peripheral nerves with the help of an acellular collagen matrix.
Martin AmanMaximilian Mayrhofer-SchmidDaniel SchwarzMartin BendszusSimeon C DaeschlerTess KlemmUlrich KneserLeila HarhausArne Hendrik BoeckerPublished in: PloS one (2023)
The supplemental application of an acellular collagen-elastin matrix showed beneficial effects in histological, radiological, and functional analysis. Therefore, applying a collagen-elastin matrix around the nerve after peripheral nerve injury or surgery may have beneficial effects on preventing scar tissue formation in the long run. This represents a feasible approach to avoid scar tissue formation in peripheral nerve surgery.