Oral deferiprone administration ameliorates cisplatin-induced nephrotoxicity in rats.

Pouran MakhdoumiKhalil AbnousSoghra MehriLeila EtemadMohsen Imenshahidi Gholamreza Karimi

Published in: The Journal of pharmacy and pharmacology (2018)

The results supported a role for iron in cisplatin-induced nephrotoxicity and TfR may serve as an important source of iron. Based on these findings, deferiprone pretreatment may play a role in preventing cisplatin-induced nephropathy in cancer patient.

Keyphrases

case report
drug induced
squamous cell carcinoma
iron deficiency
squamous cell
young adults