Antidepressant-like effect of tofisopam in mice: A behavioural, molecular docking and MD simulation study.

Nazlı Turan YücelAsaf Evrim EvrenÜmmühan KandemirÖzgür Devrim Can

Published in: Journal of psychopharmacology (Oxford, England) (2022)

This study is the first to show that tofisopam has antidepressant-like activity mediated by the serotonergic, catecholaminergic and opioidergic systems.

Keyphrases

molecular docking
major depressive disorder
molecular dynamics simulations
molecular dynamics
high fat diet induced
type diabetes
bipolar disorder
metabolic syndrome
insulin resistance