Toll-like receptor 2 gene polymorphisms in Korean women with human papillomavirus-related cervical neoplasia.

Jin Hwi KimEun Young KeyMin Jong SongSung Jong LeeChan Joo KimSoo Young HurTae Chul ParkTae Gyu KimJong Sup Park

Published in: Acta obstetricia et gynecologica Scandinavica (2016)

Our study provides the first evidence that TLR2 gene polymorphisms are associated with high-risk type HPV-related cervical neoplasia and may play an important role in susceptibility to HPV infection. Further large-scale and functional studies are needed to confirm the role of TLR2 gene polymorphisms in HPV-related cervical neoplasia.

Keyphrases

toll like receptor
high grade
inflammatory response
nuclear factor
immune response
cervical cancer screening
drug induced