Diabetic serum from older women increases adipogenic differentiation in mesenchymal stem cells.

Kendall F MoseleyMáire E DoyleSuzanne M Jan De Beur

Published in: Endocrine research (2018)

Systemic, circulating factors in the serum of older women with T2DM may promote MSC differentiation into adipocytes versus osteoblasts. Increased differentiation of MSCs into adipocytes is one possible mechanism by which T2DM increases fracture risk.

Keyphrases

mesenchymal stem cells
adipose tissue
umbilical cord
type diabetes
physical activity
bone marrow
metabolic syndrome
wound healing
insulin resistance
drug induced