Characterizing Enoxaparin's Population Pharmacokinetics to Guide Dose Individualization in the Pediatric Population.

Fernando O Carreño Jacqueline G Gerhart Victória Etges Helfer Jaydeep Sinha Karan R Kumar Carl M J Kirkpatrick Christoph P Hornik Daniel Gonzaleznull null

Published in: Clinical pharmacokinetics (2024)

Using real-world data and PopPK modeling, enoxaparin's pharmacokinetics were characterized in pediatric patients. Using FFM and twice-daily dosing might reduce the risk of overdosing, especially in children with obesity.

Keyphrases

venous thromboembolism
insulin resistance
metabolic syndrome
weight loss
young adults
type diabetes
electronic health record
physical activity
weight gain
high fat diet induced
big data
machine learning
skeletal muscle
data analysis