In vivo detection of carnosine and its derivatives using chemical exchange saturation transfer.
Solène BardinMichele LecisDavide BoidoCéline BoutinGiovanna BaronGiancarlo AldiniPatrick BerthaultFawzi BoumezbeurLuisa CiobanuPublished in: Magnetic resonance in medicine (2022)
The robustness of the CEST-linescan approach and the favorable conditions for CEST at ultra-high magnetic field allowed the in vivo CEST MR detection of carnosine and related peptides. This approach could be useful to investigate noninvasively the (patho)-physiological roles of these molecules.