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Cefepime pharmacokinetics in critically ill children and young adults undergoing continuous kidney replacement therapy.

Kathryn PaviaH Rhodes HambrickKelli PaicePeter TangNieko PuntJennifer KaplanStuart L GoldsteinAlexander A VinksTomoyuki MizunoSonya C Tang Girdwood
Published in: The Journal of antimicrobial chemotherapy (2023)
Since most patients failed to attain stringent targets of 100% fT > 4×  MIC, model-informed precision dosing may benefit such patients.
Keyphrases
  • young adults
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • replacement therapy
  • peritoneal dialysis
  • patient reported outcomes
  • smoking cessation