Androgen Receptor Splice Variant 7 in Asian Patients With Metastatic Castration-Resistant Prostate Cancer.
Daniel Jia Ming AngJohan W K ChanWhee Sze OngHui Shan TanQuan Sing NgJohn YuenKenneth ChenKae Jack TaySiew Wei WongMarniza SaadMasayoshi NagataShigeo HoriePhichai ChansriwongChi-Fai NgAlvin S C WongMatthew Chin Heng ChuaChee Keong TohMin-Han TanTony Kiat Hon LimAli Asgar Saleem BhagatRavindran KanesvaranPublished in: JCO precision oncology (2024)
In this study, the incidence of ARV-7 positivity in Asian patients with mCRPC was shown to be similar to the global population. Patients with ARV-7 positivity appear to have more aggressive disease with numerically worse PSA PFS and OS. Further prospective studies are needed to fully characterize the relationship that ARV-7 positivity has on prognosis of Asian patients with mCRPC.
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