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Elucidating Hexanucleotide Repeat Number and Methylation within the X-Linked Dystonia-Parkinsonism (XDP)-Related SVA Retrotransposon in TAF1 with Nanopore Sequencing.

Theresa LüthJoshua LaβSusen SchaakeInken WohlersJelena PozojevicRoland Dominic Go JamoraRaymond L RosalesNorbert BrüggemannGerard SaranzaCid Czarina E DiestaKathleen SchlüterRonnie TseCharles Jourdan ReyesMax BrandHauke BuschChristine KleinAna WestenbergerJoanne Trinh
Published in: Genes (2022)
Nanopore sequencing can reliably detect SVA hexanucleotide repeat numbers, methylation and, lastly, variation in the repeat motif.
Keyphrases
  • single molecule
  • single cell
  • dna methylation
  • genome wide
  • deep brain stimulation
  • early onset
  • drug induced