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Novel and replicated clinical and genetic risk factors for toxicity from high-dose methotrexate in pediatric acute lymphoblastic leukemia.

Mark C ZobeckMelanie Brooke BernhardtKala Y KamdarKaren R RabinPhilip J LupoMichael E Scheurer
Published in: Pharmacotherapy (2023)
These predictors of MTX toxicities may allow for more precise individualized toxicity risk prediction.
Keyphrases
  • high dose
  • acute lymphoblastic leukemia
  • low dose
  • stem cell transplantation
  • oxidative stress
  • allogeneic hematopoietic stem cell transplantation
  • oxide nanoparticles
  • copy number
  • acute myeloid leukemia