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Association between Ancestry-Specific 6q25 Variants and Breast Cancer Subtypes in Peruvian Women.

Valentina A ZavalaSandro CasavilcaJeannie Navarro-VásquezCarlos A CastañedaHenry Leonidas GómezZaida MoranteMónica J CalderónJulio E AbugattasHenry L GómezHugo A FuentesRuddy Liendo-PicoagaJose M CotrinaClaudia MongeSilvia P NeciosupScott HuntsmanDonglei HuSixto E SanchezMichelle A WilliamsAngel Núñez-MarreroLenin GodoyAaron HechmerAdam B OlshenJulie DutilElad ZivJovanny ZabaletaBizu GelayeJule VasquezMarco Gálvez-NinoDaniel Y Enriquez-VeraTatiana VidaurreLaura Fejerman
Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2022)
These results could inform functional analyses to understand the mechanism by which rs140068132-G reduces risk of breast cancer development in a subtype-specific manner. They also illustrate the importance of including diverse individuals in genetic studies.
Keyphrases
  • copy number
  • breast cancer risk
  • polycystic ovary syndrome
  • genome wide
  • type diabetes
  • pregnancy outcomes
  • pregnant women
  • metabolic syndrome
  • dna methylation
  • young adults
  • adipose tissue