The current status of gene expression profilings in COVID-19 patients.

Mirolyuba IlievaMax TschaikowskiAndrea VandinShziuka Uchida

Published in: Clinical and translational discovery (2022)

Based on the bulk and scRNA-seq data analysis, severe COVID-19 patients display shifts in cell populations, especially those of leukocytes and monocytes, possibly leading to cytokine storms and immune silence. These RNA-seq data form the foundation for further gene expression analysis using samples from individuals suffering from long COVID.

Keyphrases

rna seq
gene expression
single cell
data analysis
sars cov
current status
dna methylation
coronavirus disease
peripheral blood
respiratory syndrome coronavirus
electronic health record
dendritic cells
big data
early onset
cell therapy
immune response
stem cells
artificial intelligence