Regional Differences in Gamma-Aminobutyric Acid and Glutamate Concentrations in the Healthy Newborn Brain.
Sudeepta K BasuS PradhanScott D BarnettMark MikkelsenKushal KapseJ MurnickJ L QuistorffC A LopezAdre du PlessisCatherine LimperopoulosPublished in: AJNR. American journal of neuroradiology (2021)
We report normative regional variations and temporal trends of in vivo gamma-aminobutyric acid and glutamate concentrations reflecting the functional and maturational status of 3 distinct brain regions of the neonate. These measures will serve as important normative values to allow early detection of subtle neurometabolic alterations in high-risk neonates.