Clinical pre-test probability for obstructive coronary artery disease: insights from the European DISCHARGE pilot study.
Sarah FegerPaolo IbesAdriane E NappAlexander LembckeMichael LauleHenryk DregerBjörn BokelmannGershan K DavisGiles RoditiIgnacio DiezStephen SchröderFabian PlankPal Maurovich-HorvatRadosav VidakovicJosef VeselkaMalgorzata Ilnicka-SuckielAndrejs ErglisTeodora BenedekJosé Rodriguez-PalomaresLuca SabaKlaus F KofoedMatthias GutberletFilip AđićMikko PietiläRita FariaAudrone VaitiekieneJonathan D DoddPatrick DonnellyMarco FranconeCezary KepkaBalazs RuzsicsJacqueline Müller-NordhornPeter SchlattmannMarc DeweyPublished in: European radiology (2020)
https://www.clinicaltrials.gov/ct2/show/NCT02400229 KEY POINTS: • Clinical pre-test probability calculation using the initial and updated D+F model overestimates the prevalence of obstructive CAD identified by ICA and CT. • Overestimation of disease prevalence is higher for the initial D+F compared with the updated D+F. • Diagnostic accuracy of PTP assessment varies strongly between different clinical sites throughout Europe.