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Comparison of non-invasive assessment of liver fibrosis in patients with alpha1-antitrypsin deficiency using magnetic resonance elastography (MRE), acoustic radiation force impulse (ARFI) Quantification, and 2D-shear wave elastography (2D-SWE).

Rolf ReiterMartin WetzelKarim HameschPavel StrnadPatrick AsbachMatthias HaasBritta SiegmundChristian TrautweinBernd HammDieter KlattJürgen BraunIngolf SackHeiko Tzschätzsch
Published in: PloS one (2018)
The high correlation and consistent identification of patients with pathologically increased SWS using MRE, ARFI quantification, and 2D-SWE suggest that elastography has the potential to become a suitable imaging tool for the assessment of AATD-related liver fibrosis. These promising results provide motivation for further investigation of non-invasive assessment of AATD-related liver fibrosis using elastography.
Keyphrases
  • liver fibrosis
  • magnetic resonance
  • high resolution
  • computed tomography
  • magnetic resonance imaging
  • risk assessment
  • single molecule
  • radiation therapy
  • climate change
  • radiation induced
  • drug induced