Comparison of non-invasive assessment of liver fibrosis in patients with alpha1-antitrypsin deficiency using magnetic resonance elastography (MRE), acoustic radiation force impulse (ARFI) Quantification, and 2D-shear wave elastography (2D-SWE).
Rolf ReiterMartin WetzelKarim HameschPavel StrnadPatrick AsbachMatthias HaasBritta SiegmundChristian TrautweinBernd HammDieter KlattJürgen BraunIngolf SackHeiko TzschätzschPublished in: PloS one (2018)
The high correlation and consistent identification of patients with pathologically increased SWS using MRE, ARFI quantification, and 2D-SWE suggest that elastography has the potential to become a suitable imaging tool for the assessment of AATD-related liver fibrosis. These promising results provide motivation for further investigation of non-invasive assessment of AATD-related liver fibrosis using elastography.