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The black honey bee genome: insights on specific structural elements and a first step towards pangenomes.

Sonia E EynardChristophe KloppKamila Canale-TabetWilliam MarandeCéline VandecasteeleCéline RoquesCécile DonnadieuQuentin BooneBertrand ServinAlain Vignal
Published in: Genetics, selection, evolution : GSE (2024)
Our new assembly for the Apis mellifera mellifera honey bee subspecies demonstrates the utility of multiple high-quality genomes for the genotyping of structural variants, with a test case on two insertions and deletions. It will therefore be an invaluable resource for future studies, for instance by including structural variants in GWAS. Having used a single haploid drone for sequencing allowed a refined analysis of very large tandem repeat arrays, raising the question of their function in the genome. High quality genome assemblies for multiple subspecies such as presented here, are crucial for emerging projects using pangenomes.
Keyphrases
  • genome wide
  • copy number
  • dna methylation
  • single cell
  • high throughput
  • quality improvement
  • embryonic stem cells
  • genetic diversity