Elimination of macrophage-entrapped antibiotic-resistant bacteria by a targeted metal-organic framework-based nanoplatform.

Xuemeng LiuQingqing DengLu ZhangYanjuan SangKai DongJinsong Ren Xiaogang Qu

Published in: Chemical communications (Cambridge, England) (2021)

A novel metal-organic framework-based platform was designed and constructed for photosensitizer delivery for the elimination of intracellular antibiotic-resistant bacteria. With the merit of targeting and internalizing ability, the system could kill the stealthy bacteria efficiently under light irradiation.

Keyphrases

metal organic framework
cancer therapy
photodynamic therapy
adipose tissue
wastewater treatment
radiation therapy
reactive oxygen species
drug release
single cell