Electrosprayed Polymeric Nanospheres for Enhanced Solubility, Dissolution Rate, Oral Bioavailability and Antihyperlipidemic Activity of Bezafibrate.
Ru SunChengwu ShenShumaila ShafiqueOmer MustaphaTalib HussainIkram Ullah KhanYasir MehmoodKhaleeq AnwerYasser ShahzadPervaiz Akhtar ShahPublished in: International journal of nanomedicine (2020)
The optimized formulation consisting of bezafibrate, PVP K30 and cremophor ELP (1/12/1.5, w/w/w) might be a capable drug delivery system for orally administering poorly water-soluble bezafibrate with improved bioavailability and antihyperlipidemic effects.