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Transcriptomic and proteomic profiling revealed reprogramming of carbon metabolism in acetate-grown human pathogen Candida glabrata.

Shu Yih ChewAlistair J P BrownBenjamin Yii Chung LauYoke Kqueen CheahKok Lian HoDoblin SandaiHassan YahayaLeslie Thian-Lung Than
Published in: Journal of biomedical science (2021)
Here, we presented the first global metabolic responses of C. glabrata to alternative carbon source using transcriptomic and proteomic approaches. These findings implicated that reprogramming of the alternative carbon metabolism during glucose deprivation could enhance the survival and persistence of C. glabrata within the host.
Keyphrases
  • candida albicans
  • single cell
  • biofilm formation
  • rna seq
  • endothelial cells
  • label free
  • type diabetes
  • insulin resistance
  • cystic fibrosis
  • staphylococcus aureus
  • weight loss